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Single nucleotide polymorphisms (SNPs) are the most frequently occurring genetic variation in the human genome, with the total number of SNPs reported in public SNP databases currently exceeding 9 million. This SNPs are used to quickly and easily identify heritable differences among individual plants, animals, or humans within a population. Furthermore, SNPs are important markers in many studies that link sequence variations to phenotypic changes, such studies are expected to advance the understanding of human physiology and explain the molecular bases of diseases. For this reason, over the past several years a great deal of effort has been dedicated to developing accurate, rapid and cost-effective technologies for SNP analysis, yielding a large number of distinct approaches. Moreover, SNP genotyping has a broad range of applications in a number of industries such as pharmaceuticals, research and agricultural biotechnology. The use of SNP genotyping is growing rapidly from personalized genetic testing in plant and animal biotechnology.
The single nucleotide polymorphism market is driven by key factors such as rising applications of SNPs in several life sciences & biotechnology aspects, advancement in agricultural biotechnology, diagnostic research & pharmaceuticals and rising prevalence of various chronic diseases. However, huge cost of research and development and unsatisfactory reimbursement policies are some of the factors hampering the market growth. Besides, new market potential in developing countries is the major opportunities for this market.
The single nucleotide polymorphism market is segmented by technology, application and geography
The technologies discussed in this market are SNP Genechips and Microarrays, TaqMan Assay (Allelle-Specific Hybridization), SNP genotyping based upon Pyrosequencing, SN Plex based upon Applied Biosystems, Masarray MALDI-TOF, RFLP (Restricted Fragment Length Polymorphism), SSCP (Single-Strand Conformation Polymorphism) and ARMS (Amplication Refractory Mutation System). RFLP (Restriction Fragment Length Polymorphism) is a molecular method of genetic analysis that allows individuals to be identified based on unique patterns of restriction enzyme cutting in specific regions of DNA. Moreover, single-strand conformational polymorphism (SSCP) analysis is a simple and sensitive technique for mutation detection and genotyping.
Various application were studied in this report such as animal genetics, plant improvement, diagnostic research, aquaculture, pharmaceuticals and pharmacogenomics, agricultural biotechnology and animal livestock & breeding. In plant improvement application, using SNP genotyping, selective breeding is accelerated by allowing traits to be identified and selected prior to growing the organism to maturity which saves time and money.
On the basis of geography, the single nucleotide polymorphism market is segmented into North America, Europe, Asia-Pacific and Rest of the world. North America region accounted for the largest market share in single nucleotide polymorphism genotyping market in 2018, due to rising commercial research in personalized medicines, availability of better R&D facilities and the presence of advanced technologies. However, Asia-Pacific is anticipated to be the fastest-growing region for the single nucleotide polymorphism genotyping market, primarily due to the development of government policies, growing focus on research and development activities in the health care sector and rising incidences of targeted diseases in this region.
Some of the major players operating in the animal genetics market includes Beckman Coulter, Bio-Rad Laboratories, GE Healthcare, Affymetrix Inc., Sequenom, Inc., Roche Holding AG, Qiagen, Fluidigm Corporation, Agilent Technologies and Thermo Fisher Scientific Inc. Leading companies have invested massive capital in research & development and mergers & acquisitions activities to develop innovative products in the market.
January 2017: Illumina, Inc. and Bio-Rad Laboratories, Inc. announced the launch of the Illumina Bio-Rad Single-Cell Sequencing Solution at the J.P. Morgan Healthcare Conference. The comprehensive solution is the first next-generation sequencing (NGS) workflow for single-cell analysis, providing researchers the ability to investigate the coordinated contribution of individual cells in tissue function, disease progression, and therapeutic response.
April 2015: Affymetrix and MTI Ltd., through its wholly-owned subsidiary, EverGene Ltd., announced the collaboration in genetic research and personal genomics services in Japan. With the support of leading academics and through this collaboration, MTI/EG plans to further expand their business in the healthcare field.
The single nucleotide polymorphism market is segmented by technology, application and geography. The technologies discussed in this market are SNP Genechips and Microarrays, TaqMan Assay (Allelle-Specific Hybridization), SNP genotyping based upon Pyrosequencing, SN Plex based upon Applied Biosystems, Masarray MALDI-TOF, RFLP (Restricted Fragment Length Polymorphism), SSCP (Single-Strand Conformation Polymorphism) and ARMS (Amplication Refractory Mutation System). RFLP (Restriction Fragment Length Polymorphism) is a molecular method of genetic analysis that allows individuals to be identified based on unique patterns of restriction enzyme cutting in specific regions of DNA. Moreover, single-strand conformational polymorphism (SSCP) analysis is a simple and sensitive technique for mutation detection and genotyping. Various application were studied in this report such as animal genetics, plant improvement, diagnostic research, aquaculture, pharmaceuticals and pharmacogenomics, agricultural biotechnology and animal livestock & breeding. In plant improvement application, using SNP genotyping, selective breeding is accelerated by allowing traits to be identified and selected prior to growing the organism to maturity which saves time and money. On the basis of geography, the single nucleotide polymorphism market is segmented into North America, Europe, Asia-Pacific and Rest of the world. North America region accounted for the largest market share in single nucleotide polymorphism genotyping market in 2018, due to rising commercial research in personalized medicines, availability of better R&D facilities and the presence of advanced technologies. However, Asia-Pacific is anticipated to be the fastest-growing region for the single nucleotide polymorphism genotyping market, primarily due to the development of government policies, growing focus on research and development activities in the health care sector and rising incidences of targeted diseases in this region.
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