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Immunohistochemistry (IHC) is a technique for identifying cellular or tissue constituents (antigens) by means of antigen-antibody interactions, the site of antibody binding being identified by direct labelling of the antibody, or by use of secondary labelling method. IHC is a well-established ancillary technique to facilitate the diagnosis of infectious and neoplastic processes in animals. Immunohistochemical studies have traditionally focused on markers of specific cell and/or tumour type as aids in the diagnosis of specific tumours.
The applications of IHC have recently been expanded explosively as more and more molecules involved in pathogenesis, diagnosis, and treatment of diseases are discovered. The unique feature that makes IHC stand out among many other laboratory tests is that it is performed without destruction of histologic architecture, and thus the assessment of an expression pattern of the molecule is possible in the context of microenvironment.
The global immunohistochemistry market is observing significant growth owing to rising prevalence of chronic diseases and rapidly growing elderly population IHC plays a vital role in disease diagnosis by predicting prognosis of tumors. It is used in identification of enzymes, tumour suppressor genes, antigens, and tumour cell proliferation, among others.
Immunohistochemistry is more advantageous than traditional enzyme staining techniques since it involves specific antigen-antibody reactions. The market is further boosted by rapid increase in healthcare spending and a changing healthcare infrastructure with better medical practice and care facilities. Furthermore, rising popularity of targeted immunotherapy and biologic therapy for anticancer drug development and increasing Food and Drug Administration (FDA) approvals would further provide significant growth opportunities to this market in the future. However, the market is hindered by limited reimbursements and implementation of excise duty by the U.S. government.
The report analyses the global immunohistochemistry market based on product, application, end user and geography.
Based on product, the market is categorized into antibodies, equipment, reagents and kits. The antibodies are further segmented into primary antibodies and secondary antibodies. Several equipment’s considered in this market are slide scanners, slide staining systems, tissue microarrays, tissue processing systems and others. Moreover, the reagents included in the market are blocking sera & reagents, chromogenic substrates, diluents, fixation reagents, histological stains, organic solvents, proteolytic enzymes and stabilizers.
The immunochemistry market has applications in diagnostics and drug testing. The diagnostic segment majorly comprises autoimmune diseases, cancer, cardiovascular diseases, diabetes mellitus, infectious diseases and nephrological diseases. Immunochemistry techniques play a vital role in drug development process for testing drug efficacy through detection of up or down regulation in disease targets. According to the American Cancer Society, around 1,688,780 new cases of cancer were reported in 2017. In addition, the WHO’s International Agency for Research on Cancer (IARC) predicts the global burden of cancer to multiply and reach 22 million in the coming years.
Furthermore, various end users of this market are categorized into hospitals & diagnostic laboratories, research institutes and other end users including contract research organization and forensic laboratories. Immunohistochemistry has various advantages over traditional staining techniques. Hence, it is an important technique used in research institutes.
By geography, the global immunohistochemistry market is studied across the countries of key regions such as, North America, Europe, Asia Pacific and rest of the world. In 2018, North America held the largest revenue share mainly due to factors such as rising prevalence of chronic diseases, matured biotechnology market and increasing commercialization of the immunohistochemistry products and developed research and healthcare institutions. Asia Pacific is expected to be the fastest growing segment, owing to rapid growth of biotech industry in developed economies such as Japan and Australia coupled with emerging economies like India and China.
The leading immunohistochemistry market players are Abcam PLC, Agilent Technologies, Inc., Bio SB, Bio-Rad Laboratories, Inc., Cell Signaling Technology, Inc., Danaher Corporation, Hoffmann-LA Roche AG, Merck Millipore and Perkinelmer, Inc. The company’s focus on alliances, strategic planning, new product launches, and research activities to achieve widespread growth. For instance, in 2017, PerkinElmer announced the launch of Vectra Polaris Automated Quantitative Pathology Imaging System, which is designed to provide researchers with an enhanced understanding of cancer immunotherapy approaches.
The global immunohistochemistry market is segmented based on product, application, end user and geography. Based on product, the market is categorized into antibodies, equipment, reagents and kits. The antibodies are further segmented into primary antibodies and secondary antibodies. Several equipment’s considered in this market are slide scanners, slide staining systems, tissue microarrays, tissue processing systems and others. Moreover, the reagents included in the market are blocking sera & reagents, chromogenic substrates, diluents, fixation reagents, histological stains, organic solvents, proteolytic enzymes and stabilizers.
The immunochemistry market has applications in diagnostics and drug testing. The diagnostic segment majorly comprises autoimmune diseases, cancer, cardiovascular diseases, diabetes mellitus, infectious diseases and nephrological diseases. Immunochemistry techniques play a vital role in drug development process for testing drug efficacy through detection of up or down regulation in disease targets.
Furthermore, various end users of this market are categorized into hospitals & diagnostic laboratories, research institutes and other end users including contract research organization and forensic laboratories.
By geography, the global immunohistochemistry market is studied across the countries of key regions such as, North America, Europe, Asia Pacific and rest of the world. In 2018, North America held the largest revenue share mainly due to factors such as rising prevalence of chronic diseases, matured biotechnology market and increasing commercialization of the immunohistochemistry products and developed research and healthcare institutions.
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