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Apoptosis is a form of cell death characterized by several features including cell shrinkage, membrane blebbing, chromosome condensation, nuclear fragmentation, DNA laddering and the eventual engulfment of the cell by phagosomes. Moreover, a wide variety of cellular proteins, including cell surface receptors, adaptors, proteases and mitochondrial components, regulate a fine balance between cell survival and death by apoptosis. Furthermore, mutations of these sensor and effector proteins may tip the balance, resulting in the uncontrolled survival and proliferation of cancer cells. Uncovering apoptosis mechanisms will result in new strategies to exploit apoptosis for therapeutic benefit. Additionally, a large number of methods are available in the identification of apoptotic cells and the analysis of the morphological, biochemical and molecular changes that take place during this universal biological process have been developed. It is observed through flow cytomerty, spectrometry, and various other techniques in research institutes, diagnostic laboratories.
The apoptosis assays market has gained significant growth due to the remarkable increase in spending on cancer research across the globe, rising incidence and prevalence of chronic and infectious diseases and growing cell-based research. Moreover, technological advancements in apoptosis assays is also the major factors contributing to the growth of the apoptosis assays market. However, high investments required for research and development and lack of skilled technicians are the key factors hampering the apoptosis assays market growth.
The apoptosis assays market is divided by product, detection technology, application, end user and geography
Based on product, the apoptosis assays market is classified into assay kits, reagents, microplates and instruments. Furthermore, assay kits are sub segmented into caspase assays, annexin V & cell permeability assays, DNA fragmentation assays and mitochondrial assays. The demand for assay kits has increased significantly over the past few years, owing to surge in cell-based applications in drug discovery and rise in technological advancements in assays kit methodologies. In addition, adoption of high-throughput screening methods and increase in R&D investment further drive the assay kits segment.
The detection technologies discussed in this market are flow cytometry, cell imaging & microscopy and spectrophotometry. The cell imaging and microscopy segment is projected to witness the highest CAGR due to its growing adoption of cell imaging and microscopy in diagnostic laboratories, drug discovery applications, and basic research. Moreover, increasing funding for development of efficient cell imaging techniques is also anticipated to boost the market over the forecast period.
Various application were studied in this report such as drug discovery & development, clinical & diagnostic applications, basic research and stem cell research. Owing to the increasing number of stem cell research activities and rising investments in stem cell research. Also government initiatives are anticipated to surge the number of cell-based research activities, which in turn will support the growth of the stem cell application segment.
Various end user were studied in this report such as pharmaceutical & biotechnology companies, hospital & diagnostic laboratories and academic & research institutes. The pharmaceutical and biotechnology companies segment is expected to account for the largest share in 2018, due to the increasing number of research & development activities undertaken by these companies for the development of biopharmaceutical products.
By geography, the apoptosis assays market is studied across the countries of key regions such as, North America, Europe, Asia Pacific, Latin America and Middle East & Africa. Among these, the North America region dominated the apoptosis assays market in 2018, owing to rising government investments in biotechnology and biomedical areas. In addition, increased research in the field of cell based therapy is also supporting in the growth of apoptosis assays in the region. However, the Asia-Pacific region is projected to grow at a fastest CAGR during the forecast period, with their low-cost manufacturing advantage, China and India are regarded as the most profitable manufacturing and R&D locations by manufacturers.
The report provides widespread competitive analysis and profiles of major market players, such as Merck KGaA, Thermo Fisher Scientific, Bio-Rad Laboratories, GE Healthcare, Danaher Corporation, Becton, Dickinson and Company, Sartorius AG, Geno Technology, GeneCopoeia, Inc., Bio-Techne Corporation, BioTek Instruments, PerkinElmer, Promega Corporation, Biotium, Abcam plc, Canvax, Abnova, and Creative Bioarray. Market players are involved in new product launches and acquisitions to exploit maximum revenue potential in global apoptosis assays market.
The apoptosis assays market is divided by Product, detection technology, application, end user and geography. Based on product, the apoptosis assays market is classified into assay kits, reagents, microplates and instruments. Furthermore, assay kits are sub segmented into caspase assays, annexin v and cell permeability assays, DNA fragmentation assays and mitochondrial assays. The demand for assay kits has increased significantly over the past few years, owing to surge in cell-based applications in drug discovery and rise in technological advancements in assays kit methodologies. In addition, adoption of high-throughput screening methods and increase in R&D investment further drive the assay kits segment.
On the basis of detection technologies the market is classified into flow cytometry, cell imaging & microscopy and spectrophotometry. The cell imaging and microscopy segment is projected to witness the highest CAGR due to its growing adoption of cell imaging and microscopy in diagnostic laboratories, drug discovery applications, and basic research. Moreover, increasing funding for development of efficient cell imaging techniques is also anticipated to boost the market over the forecast period.
By application this report is bifurcated into drug discovery & development, clinical & diagnostic applications, basic research and stem cell research. Owing to the increasing number of stem cell research activities and rising investments in stem cell research. Also government initiatives are anticipated to surge the number of cell-based research activities, which in turn will support the growth of the stem cell application segment.
Based on end user, the market is classified into pharmaceutical & biotechnology companies, hospital & diagnostic laboratories and academic & research institutes. The pharmaceutical and biotechnology companies segment is expected to account for the largest share in 2018, due to the increasing number of research & development activities undertaken by these companies for the development of biopharmaceutical products.
Geographically, the apoptosis assays market is studied across the countries of key regions such as, North America, Europe, Asia Pacific, Latin America and Middle East & Africa. Among these, the North America region dominated the apoptosis assays market in 2018, owing to rising government investments in biotechnology and biomedical areas. In addition, increased research in the field of cell based therapy is also supporting in the growth of apoptosis assays in the region. However, the Asia-Pacific region is projected to grow at a fastest CAGR during the forecast period, with their low-cost manufacturing advantage, China and India are regarded as the most profitable manufacturing and R&D locations by manufacturers.
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