Pharmaceutical excipients are the substances which are added along with the active pharmaceutical ingredient to help easy delivery of drug at target site. Excipients do not have direct therapeutical action but to aid the manufacturing process, to protect, support or enhance stability, or for bioavailability or patient acceptability. The excipients are inert and simple to active and complex substances that can be difficult to characterize. They act as the carrier (vehicle or basis) or as a component of the carrier of the active substances. It plays vital role in drug delivery within the body. It assist in product identification, and enhance any attribute of the overall safety. Purpose of addition of excipients are long term stabilization of formulations.
The factors that impeding bone growth stimulator market are increase in the number of chronic diseases and greater awareness towards physical well-being. Besides this, rising incidence of lifestyle diseases such as diabetes and obesity-related disorders and government initiatives towards healthcare services will fuel market growth in upcoming years. Nevertheless, cost and time-intensive drug development process and lack of separate guidelines for manufacturing and approval of excipients are the major restraining factor that could hamper the growth of the market.
The COVID 19 outbreak causes ill impact on many industries and also had significant impact on the healthcare market. As the rise in COVID 19 cases, for prevention purpose government has announced lockdown in many countries which lead to disturbance in manufacturing and supply of raw materials in various countries. But for COVID 19 treatment demand for drugs such as Remdesivir and hydroxychloroquine has increased which will boosts market growth. During this pandemic process of drug development and manufacturing of raw materials has increased. Hence, COVID 19 negligible impacted the growth of the overall market in 2020.
The study analyses Europe Pharmaceutical Excipients Market based on product, functionality, formulations and country.
The various products included in the pharmaceutical excipients market is categorized into organic and inorganic chemicals. Organic chemicals are further categorized into carbohydrates and petrochemicals. Inorganic chemicals are sub-segmented into Calcium Phosphates, Calcium Carbonate, Calcium Sulfate, Halites and Metallic Oxides. The organic chemicals segment is expected to contribute to increasing demand for excipients over the assessment period due to , increasing demand for superior quality excipients and rise in demand for drugs lead to increase in manufacturing process.
Depending on the functionality the pharmaceutical excipients market is classified into fillers & diluents, binders, suspending & viscosity agents, flavoring agents & sweeteners, coating agents, colorants, disintegrants, lubricants & glidants, preservatives, emulsifying agents, and other functionalities. The fillers and diluents segment expected to account for the largest share of the market in 2020. The factors driving segmental growth are increased requirement of excipients in the local industry because, diluents acts as a disintegrants in dispersible and orally disintegrating tablet and also increase volume of formulations.
According to the formulations the pharmaceutical excipients market is bifurcated into oral, topical, parenteral, and other formulations. The oral formulations segment dominated the market in 2020 and is expected to maintain its dominance during the forecast period 2021-2027. The factors driving market growth are rise in demand for excipients in oral dosage forms as it requires more amount of excipients than other forms during the drug manufacturing process.
Country wise, the study is comprised of the key countries such as the UK, Germany, France, Italy, Spain and Rest of Europe. The UK held the largest market share of Europe pharmaceutical excipients market and is likely to dominate the market over the estimated time frame. Owing to the factors responsible for the market growth in UK are rise in demand for excipient during manufacturing process.
The major key players of market includes Ashland Global Holdings (US), BASF SE (Germany), DuPont (US), Roquette Feres (France), Evonik Industries AG (Germany), Associated British Foods (UK), Archer Daniels Midland Company (US), Lubrizol Corporation (US), and Croda International (UK), Innophous Holdings (US), Kerry Group (Ireland), WACKER Chemie AG (Germany), Colorcon (US), DFE Pharma (Germany), JRS Pharma (Germany), and Air Liquide (France).
July 2020: Colorcon launched the Acryl-EZE II film coating line which extends the pH range covered by its enteric coatings.
October 2020: Evonik launched the EUDRATEC Fasteric releases, an advanced oral drug delivery technology that provides enteric protection ollowed by rapid, homogeneous release for effective targeting of the upper small intestine.
December 2018: Roquette (France) signed an agreement with Thermo Fisher. Roquette signed an agreement with ThermoFisher Scientific (US), which gives Thermo the right to distribute Roquette’s products in the US and Canada. This will provide further market access to Roquette.
May 2019, Ashland announced the launch of Aquarius Nutra TF, which provides titanium oxide-based coating to tablets in the European market.
The study analyses Europe pharmaceutical excipients market product, functionality, formulations and country. Pharmaceutical excipients are substances other than the active pharmaceutical ingredient (API) that have been appropriately evaluated for safety and are intentionally included in a drug delivery system. Various pharmaceutical excipients included in this report are fillers & diluents, binders, suspending & viscosity agents, flavoring agents & sweeteners, coating agents, colorants, disintegrants, lubricants & glidants, preservatives, emulsifying agents, and other functionalities. The primary growth factors behind the market growth are growth of the pharmaceuticals market backed by functional excipients and surge in the generics market. Increasing uptake of biopharmaceuticals will drive market growth in upcoming years. The established safety and efficacy of excipients in dosage forms is expected to impede market growth over the forecast period 2021-2027. The country wise study comprises countries like UK, Germany, France, Italy and rest of Europe. The UK held the largest market share of Europe pharmaceutical excipient market and is likely to dominate the market over the estimated time frame.
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