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In vitro toxicity testing studies the effects of toxic chemical substances on cultured cells or micro-tissues. It is used primarily to detect potentially hazardous chemicals in the early stages of development of new pharmaceuticals or agrichemicals. The final goal of toxicology is to assess risk for human of chemicals introduced newly into the market or chemicals existing in our environment for many years.
The invitro toxicology market is driven by factors like ethical issues concerning the use of animals for testing, ban on animal testing on cosmetic products etc. Moreover, support from regulatory bodies regarding the approval of in vitro tests, and the cost effectiveness of in vitro toxicology testing boost the growth of the market. Further advancements in vitro methodologies are driving the expansion of the worldwide in-vitro toxicology testing market.
Further, various emerging fields and techniques are contributing major new insights for understanding biologic responses to chemicals in human tissues. These advances are expected to drive the growth of the in-vitro toxicology market over forecast period.
The report analyses the global in-vitro toxicology market based on product, technology, method, application, end user and geography.
The various in vitro toxicology testing products incorporated in the study are assays, services, and reagents. The assays are further categorised into bacterial toxicity assays, enzyme toxicity assays, cell-based ELISA and western blots, receptor-binding assays, tissue culture assays etc.
The services segment is likely to grow at the significant pace to the increasing trend of outsourcing of in vitro toxicity tests by small and medium-sized pharmaceutical and cosmetics companies. These companies are tend to opt for outsourcing due to lack of infrastructure and expertise and the difficulty in procuring of reagents required for every target.
Cell culture technologies, high-throughput technologies, cellular imaging technologies and toxic genomics are the various technologies of in-vitro toxicology. There is increasing trend for the use of toxic genomics owing to factors such as the increasing importance of predictive testing, and expanding databases to facilitate to study toxicity pathways.
The in vitro toxicology includes various methods to carry out testing such as into cellular assays, biochemical assays, in-silico and ex vivo models. The ex vivo models acts as an effective alternative to animal testing for the toxicity testing of cosmetics and household products, and growing use of testing for cardio toxicity, hepatotoxicity, , nephrotoxicity, etc.
The market finds application in systemic toxicology, dermal toxicity, endocrine disruption and occular toxicity. Systemic toxicity is likely to account for major market share. Systemic circulation of the molecule is the most preferred method of drug distribution; it is also one of the major causes of toxic reactions, which may trigger multiple organs to fail.
The major end users of this market are pharmaceutical and biopharmaceutical industry, chemical industry, cosmetics and household products industry and food industry.
Based on geography, the global In-Vitro Toxicology market is segmented into North America, Europe, Asia Pacific and Rest of the World. North America accounted for the largest market share owing to the technological advancements and supportive government regulations have led to the rapid development of innovative, cost-effective testing for establishing drug, device, chemical and cosmetic safety.
Key players in the global In-Vitro Toxicology market include Bio-Rad Laboratories, Inc. Qiagen N.V. , GE Healthcare , Merck KGaA, Thermo Fisher Scientific, Inc , Charles River Laboratories International, Inc. , Catalent, Inc. , Agilent Technologies Inc, Eurofins Scientific, BioReliance, Inc., Alere, Inc., SGS S.A. , Covance, Inc., Promega Corporation and Gentronix Limited among others.
The report analyses the global in-vitro toxicology market based on product, technology, method, application, end user and geography.
The various in vitro toxicology testing products incorporated in the study are assays, services, and reagents. Cell culture technologies, high-throughput technologies, cellular imaging technologies and toxic genomics are the various technologies of in-vitro toxicology. The in vitro toxicology includes various methods to carry out testing such as into cellular assays, biochemical assays, in-silico and ex vivo models. The market finds application in systemic toxicology, dermal toxicity, endocrine disruption and occular toxicity. The major end users of this market are pharmaceutical and biopharmaceutical industry, chemical industry, cosmetics and household products industry and food industry.
Key players in the global In-Vitro Toxicology market include Bio-Rad Laboratories, Inc. Qiagen N.V. , GE Healthcare , Merck KGaA, Thermo Fisher Scientific, Inc , Charles River Laboratories International, Inc. , Catalent, Inc. , Agilent Technologies Inc, Eurofins Scientific, BioReliance, Inc., Alere, Inc., SGS S.A. , Covance, Inc., Promega Corporation and Gentronix Limited among others.
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